The goal is longevity, wellness, and disease prevention
Introduction Bayliss and Starling first described the connection between the pancreas, the gut and incretin hormones in the early part of the twentieth century ( Various approaches have since been used to extend the half-life of native GLP-1, several of which have resulted in pharmacological agents that are effective in the treatment of T2D
Despite the positive results regarding glycemic control, in which dulaglutide was superior to placebo and non-inferior to liraglutide, there was no significant weight loss in any group after 26 weeks
This is especially important for people maintaining active fitness routines alongside their weight loss treatment
These drugs work by mimicking the action of natural GLP-1 hormone, which stimulates insulin secretion in response to food intake, suppresses glucagon release, slows gastric emptying, and reduces appetite